The Hamdard Institute of Medical Sciences and Research, based in Delhi, has made a significant contribution to the medical world. Their research team has concocted a unique translucent nail lacquer, fortified with Luliconazole – an antifungal drug – dedicated to the treatment of onychomycosis. This special polymer embedded with the drug dries quickly and can be effortlessly applied similar to ordinary nail polish. Tests were carried out on bovine hooves because they share a striking resemblance with human nails in terms of their external structure. The results showed that, in a span of 24 hours, about 75% of the medication got released to the nail, thereby demonstrating its potential for extended drug delivery.
Understanding Onychomycosis
Onychomycosis is a nail infection caused by fungi, leading to discoloration, thickening and even separation from the nail bed. Generally, it affects toenails more than fingernails due to their slow growth, reduced blood supply and recorded confinement in dark, moist environments. A cornucopia of organisms can cause this condition, but dermatophytes (a type of fungi) are the chief culprits in most cases. The diagnosis process involves thorough physical examination, microscopic examination and culture test.
Treatment of Onychomycosis
The principal objective of the treatment process is to eliminate the causative organism and restore the normal appearance of the nail. The development of the novel Luliconazole-inclusive nail lacquer by Hamdard Institute researchers offers a promising solution in this regard. It ensures easier application and prolonged release of the required drug, potentially enhancing the efficacy of the treatment.
Testing and Results
The innovative nail lacquer was tested on bovine hooves to verify its medicinal potential. This was due to the similarity in the external structures of the bovine hooves and human nails, making them useful substitutes for the investigation.
Results from this experimental study were highly encouraging, with about 75% of the Luliconazole drug getting released into the nail within a 24-hour window. This clearly indicated its great capacity for longer-term drug delivery, proving its effectiveness and usefulness in treating onychomycosis.
| Fact | Details |
|---|---|
| Innovative Product | Translucent nail lacquer fortified with Luliconazole |
| Benefit | Easy Application as normal nail polish |
| Testing Material | Bovine hooves (similar outer structure to human nails) |
| Drug Release Rate | 75% of drug released within 24 hours |
The conclusion & Potential
In conclusion, the new drug-infused nail lacquer has shown promise in potentially revolutionizing the treatment for onychomycosis. Its easy application and effective prolonged drug delivery could play a critical role in overcoming the usual challenges associated with treating this common fungal nail infection.
