The Indian Pharmacopoeia Commission (IPC) has recently issued a drug safety alert about Meftal, a commonly used painkiller. The commission warns that the main component of the drug, mefenamic acid, can cause severe allergic reactions, including DRESS syndrome, which can harm internal organs.
Understanding the DRESS Syndrome
DRESS syndrome, short for Drug Rash with Eosinophilia and Systemic Symptoms, is a potential life-threatening allergic reaction primarily triggered by specific medications. It affects approximately one in ten individuals and can be deadly if not treated on time.
Also known as Drug-Induced Hypersensitivity Syndrome (DIHS), DRESS syndrome results in skin rash, high fever, swollen lymph nodes, and complications in internal organs. Recognition of symptoms and immediate withdrawal of the suspect drug are the first steps to manage this medical condition.
The Usage and Potential Side Effects of Meftal
Meftal is widely used in India as a non-steroidal anti-inflammatory drug (NSAID). It finds usage in relieving various kinds of pains, like menstrual pain, headaches, and muscle and joint pain. It is also popular among children suffering from high fever.
Despite its common use, prolonged consumption of Meftal may elevate the risk of stomach ulcers, bleeding and related complications. There are indications suggesting that the drug could have potential adverse effects on the cardiovascular system. Some health experts have pointed out potential renal complications arising from Meftal usage.
An Overview of the Indian Pharmacopoeia Commission (IPC)
The IPC is an autonomous entity under the Ministry of Health and Family Welfare. Established to set drug standards in India, the IPC continuously updates the regulations for drugs, keeping in mind the diseases prevalent in the region.
An essential role of the IPC includes publishing official documents to improve medicine quality by adding new monographs and updating existing ones in the Indian Pharmacopoeia (IP). The commission also promotes the rational use of generic medicines by publishing the National Formulary of India.
Furthermore, the IPC provides IP Reference Substances (IPRS), which are essential for identifying the article under test and determining its purity, as prescribed in IP.
Conclusion
The recent alert by the IPC on Meftal has again spotlighted the need for vigilance in drug consumption and alarmed healthcare providers about potential risks associated with common medications. As the medical community reviews the drug use, consumers must remain informed about these developments to make educated health decisions.
