Reliance Develops R-Green kit- can give COVID results in 2 hours

Reliance Life Sciences has developed an real-time reverse transcription-polymerase chain reaction (RT-PCR) kit. It claims to diagnose COVID-19 infection in about 2 hours. Presently, COVID-19 RT-PCR test takes up to 24 hours to give a diagnosis.

Key Facts

  • The kit has been developed by Computational biologists at Reliance Life Sciences a subsidiary of Reliance Industries Ltd.
  • This kit is indigenous development of the R&D scientists working at the firm.
  • They analysed more than 100 genomes of SARS-CoV-2 sequenced in India in order to design RT-PCR primers for developing quantitative-Real Time PCR kit.
  • The kit has been technically validated by ICMR for satisfactory performance. It does not approve or disapprove the kit design as well as it does not certify user-friendliness.

R-Green Kit

The kit can detect the presence of E-gene, R-gene, RdRp gene of SARS COV2 virus with Actin as an internal control. According to the ICMR results, the kit is 98.7 % sensitive and 98.8 % specific. The diagnosis time of the kit is approximately 2 hours.

Study by Reliance Life Sciences

  • The study says, the death rate for COVID-19 pandemic may significantly reduce by the end of 2020.
  • As per them, mutation occurrence of structural and non-structural proteins of SARS-CoV-2 form more than 7,000 genome sequences of SARS-CoV-2 virus from 49 countries.
  • There is an inverse correlation between the mutation rates of two proteins NSP6 and Surface glycoprotein (S) with the death rate.
  • They predicted that mutations of these two proteins will grow constantly and the death rate would drop below 0.5% by end of 2020 in cluster I countries.
  • They said, mutation rate of NSP6 and S proteins are lower than cluster I and cluster III countries.
  • Therefore, in cluster II country the death rate of COVID-19 pandemic will weaken later than cluster I and III countries.
  • Note:
  1. Cluster I countries – India and Bangladesh
  2. Cluster II country – USA
  3. Cluster III countries- Australia and New Zealand.